STAT3 plays a pivotal role in pancreatic cancer and is drawing increased attention as a potential drug target for the disease. This post will be updated periodically.
MIR506 – Sun L, Hu L, Cogdell D, Lu L, Gao C, Tian W, Zhang Z, Kang Y, Fleming JB, Zhang W. MIR506 induces autophagy-related cell death in pancreatic cancer cells by targeting the STAT3 pathway. Autophagy. 2017 Jan 25:0. doi: 10.1080/15548627.2017.1280217. PubMed PMID: 28121485.
AZD9150 – AZD9150 With MEDI4736 in Patients With Advanced Pancreatic, Non-Small Lung and Colorectal Cancer. ClinicalTrials.gov Identifier: NCT02983578