Resource – STAT3 – Pancreatic Cancer

 

STAT3 plays a pivotal role in pancreatic cancer and is drawing increased attention as a potential drug target for the disease. This post will be updated periodically.

 

STAT3 inhibitors (1)Refs

MIR506 – Sun L, Hu L, Cogdell D, Lu L, Gao C, Tian W, Zhang Z, Kang Y, Fleming JB, Zhang W. MIR506 induces autophagy-related cell death in pancreatic cancer cells by targeting the STAT3 pathway. Autophagy. 2017 Jan 25:0. doi: 10.1080/15548627.2017.1280217. PubMed PMID: 28121485.

HO-3867

Nexrutine®

Renalase

AM0010

AZD9150 – AZD9150 With MEDI4736 in Patients With Advanced Pancreatic, Non-Small Lung and Colorectal Cancer. ClinicalTrials.gov Identifier: NCT02983578

DHA – Park M, Kim H. Anti-cancer Mechanism of Docosahexaenoic Acid in Pancreatic Carcinogenesis: A Mini-review. J Cancer Prev. 2017 Mar;22(1):1-5. doi: 10.15430/JCP.2017.22.1.1. Epub 2017 Mar 30. Review. PubMed PMID: 28382280

 

 

 

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